The central nervous system is affected by an autoimmune disease known as multiple sclerosis (MS). The body's immune system begins to attack several central nervous system components, including the brain, spinal cord, and optic nerve. Even though there is no cure for MS, stem cell therapy can help patients feel better and stop the disease's development. In addition, clinical trials allow patients to participate in experimental treatments like stem cell therapy.
MS makes the body target its central nervous system for an immunological response. The myelin, a fatty coating around the nerve fibers, is harmed by this immune reaction. Additionally, it harms the myelin-producing cells and nerve fibers themselves.
The extent of MS symptoms might vary. Some people may experience just minor symptoms, while others may experience severe symptoms that may be hindering. One of the best treatments for such diseases is stem cell therapy initiated by scientists such as Dr. David Greene Arizona, which is in much demand presently.
Stem cells are a kind of cell that can develop into any other particular cell in the adult body. As they aid in the body's development of the different types of cells required, these cells are crucial to development in infancy and growth.
How can stem cells treat MS?
MS can be treated with stem cells by medical professionals. They can do stem cell transplants, in which an individual with MS receives healthy stem cells to swap certain types of cells in their body.
Different stem cell types are used in various types of stem cell treatment.
They consist of:
Autologous hematopoietic stem cell transplantation
In an autologous hematopoietic stem cell transplantation (aHSCT), the immune system is destroyed and rebuilt with the patient's hematopoietic stem cells. These stem cells can differentiate into white blood cells, red blood cells, and platelets, among other blood cells.
This approach destroys the MS; symptoms-causing immune system malfunction is destroyed and replaced with a healthy immune system.
A person receives cytotoxic therapy to eliminate the natural, malfunctioning immune system. Typically, this takes the form of chemotherapy combined with therapeutic antibodies that assist remove and killing immune system cells.
Mesenchymal stem cell therapy
MS symptoms may also be treated with mesenchymal stem cell (MSC) therapy. The clinical trial stage of this treatment is still ongoing.
MSCs have the power to encourage myelin regeneration and boost a person's immune system.
During MSC therapy, a physician extracts a patient's MSCs from their bone marrow, blood, or other tissues. They subsequently increase the quantity of these cells in a lab and reintroduce them into their body.
Before the therapy is finished, a scientist might, in some cases, treat these cells. They might do this to improve the cells' capacity to control immune responses that harm the neurological system and support their capacity to restore myelin.
Several clinical trials have been conducted to evaluate the efficacy of MSC treatment for MS patients. MSCs have shown promise in pre-clinical and clinical studies by experts like Dr. David Greene Orthopedic Surgeon for the treatment of MS. According to the review, and this is because:
- Their capacity to alter an individual's immune system
- They discharge trophic factors, substances that aid in developing the brain's neurons' capacity to differentiate into a range of other cells.
- Their capacity to regrow
Different types of stem cells
Researchers are conducting clinical trials to establish whether various types of stem cells can effectively treat MS.
The following stem cells are a few that could help treat MS:
- Hematopoietic stem cells (HSCs): These are adult stem cells that can be found in blood and bone marrow. All blood cells, as well as immune system-related cells, can be produced by them.
- Mesenchymal stem cells (MSCs): These adult stem cells can be found throughout the body, including in the fat, skin, and bone marrow. These stem cells can give rise to the cells that support the healthy function of other stem cells.
- Neural stem cells (NSCs): The myelin in the brain can be repaired by these specific stem cells. This is advantageous since MS can harm both myelin and the cells that produce myelin. Other stem cells, such as mesenchymal cells, can produce NSCs.
- Human embryonic stem cells (hESCs): These embryonic stem cells were provided. Since they can generate every type of cell in the human body spontaneously, they might be useful in the treatment of MS. Their safety is questioned since they might have the ability to grow malignancies.
Summary
An autoimmune illness with a long history is multiple sclerosis (MS). The immune system begins to assault the brain, spinal cord, and optic nerve. Weakness, difficulty walking, stiffness and muscular spasms, blurred vision, vertigo, and dizziness are just a few symptoms of MS.
Medical specialists are conducting numerous clinical trials, like Dr. David Greene Arizona, to evaluate the efficacy of these various cells.
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