Cell-based therapies, specifically ones that involve mesenchymal stem cells (MSCs) or extracellular vesicles, have become an effective tool in treating coronavirus. As multipotent and non-hematopoietic cells, MSCs can differentiate into various dermal lineages, added Dr. David Greene Arizona. Interestingly, they are present in different tissues of multiple sources that may range from many to fetal adult tissues.
Let’s plunge into the discussion to see what makes mesenchymal stem cells an excellent therapeutic strategy.
Mesenchymal Stem Cells A Therapeutic STrategy: As mesenchymal stem cells have proven benefits in regenerative medicines, they have become an excellent option to use as an effective cell-based therapy. It is because these powerful cells can regenerate and replace injured organs and tissues.
However, there is no denying that the potential of MSCs is way beyond just offering tissue repair. They can deliver numerous positive outcomes and therapeutic utilities, said Dr. David Greene. The cells contain fantastic anti-inflammatory and immunomodulatory properties in autoimmune, neurodegenerative, and cardiovascular diseases.
When using for lungs, the mesenchymal stem cells balance and maintain the inflammatory response. They can also release mediators such as angiogenic growth factors, EVs, and antimicrobial peptides. This is what makes MSCs a valuable option to treat infections like COVID-19.
MSCs also have a unique ability to show immunomodulatory capacity, attenuating and preventing the cytokine storm. The same quality works excellent to reduce mortality and morbidity. Medical professionals specializing in stem cell treatment centers consider the use of MSCs as an innovative medical approach.
Mesenchymal Stem Cells as a Strategy for COVID-19 Patients - Stem cell therapy doctors in Phoenix AZ at R3 Stem Cell use MSCs for severe and critical COVID-19 patients as a treatment option. Plus, stem cell scientists further use stem cells to understand their impact in vitro-culture conditioning methods. It helps scientists discover their clinical significance and therapeutic potential for diseases like COVID-19.
Outcomes of the latest clinical trials with Phoenix stem cell treatment for COVID-19 have shown their potential as a therapeutic strategy. MSCs derived from the umbilical cord (UCMSCs) can act as an efficient treatment for diseases primarily associated with clinical cases and supportive therapies.
Over the years, both MSCs derived from the umbilical cord and adult adipose tissues will play an important role in developing a clinical treatment for COVID-19, added David Greene Orthopedic. We say this because adult adipose tissues demonstrate an interesting multipotency to repair the tissues and reduce inflammation.
The latest studies show that it is easy to isolate MSCs from mesenchymal tissues, which manifest an excellent regenerative capacity. The cells also have basic stem cell qualities such as self-renewal, clonogenic potential, and tissue regeneration ability.
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