Skip to main content

ALS Disease Stem Cell Treatment at R3 International | Dr. David Greene

ALS disease is named after New York Yankee first baseman Lou Gehrig who developed it in 1939. More formally known as Amyotrophic Lateral Sclerosis (ALS), is a neurodegenerative disease of an unknown cause that is characterized by degeneration of motor neurons in the brain and spinal cord. It often moves very quickly from weakness in limbs to progressive paralysis and eventually, respiratory failure added Dr. David Greene R3 Stem Cell CEO. It typically occurs in the forties through seventies. is caused by a combination of genetic and environmental factors. It has been very difficult to find effective treatments for ALS.


What are Stem cells? - Stem cells are the body’s own cells from which all other cells with specialized functions are generated. These daughter cells either become new stem cells or differentiate into specialized cells (blood cells, brain cells, heart muscle, etc.) There are several sources of stem cells:

  • Embryonic stem cells: come from 3 – 5 days old embryos. These are pluripotent stem cells and can divide into more stem cells or can become any type of cell in the body, and can be used to regenerate or repair diseased tissue and organs.
  • Adult stem cells: found in most adult tissues, such as bone marrow or fat. They have a more limited ability to differentiate into various cells of the body. Lately, it has been found that adult stem cells may be able to create unrelated types of cells, such as bone marrow stem cells forming heart muscle cells.
  • Perinatal stem cells: are found in amniotic fluid and umbilical cord blood.

Stem cell treatment for ALS - There has been a lot of research on using stem cells for the treatments for ALS. Induced pluripotent stem cells (iPSCs) have been used as a source of motor neurons from individual ALS patients to study why and how motor neurons degenerate in ALS, added Dr. David Greene Arizona. Both upper and lower motor neurons, as well as astrocytes, can be made from iPSCs.


Motor neurons derived from iPSCs can be tracked over time to understand if a test compound has a positive or negative effect. Furthermore, comparing the motor neurons derived from iPSCs can help understand patients’ clinical picture. More importantly, stem cells can also help in treating the disease. They can be used to produce cells that motor neurons in the brain and spinal cord.

 

Several trials are underway that testing new approaches that use stem cells for ALS treatment. One of these includes using mesenchymal stem cells that can be taken from the patient’s own bone marrow or fat tissue and then modified to enhance their support for dying motor neurons, added David Greene Orthopedic. Another trial is focused on studying the effects of injecting muscle tissue into the fluid surrounding the brain and spinal cord. 


A recent study in JAMA Neurology reported that the treatment was safe and well-tolerated, resulting in a decreased rate of disease progression during six months after the injections, as compared to six months before treatment. There is still a lack of high-quality evidence to guide the clinical use of stem cell therapies for the treatment of ALS in the clinic, but the results of recent and current trials have been very encouraging.

Labels:

Comments

Post a Comment

Popular posts from this blog

Reasons To Choose Stem Cell Therapy Over Surgery | Dr. David Greene Arizona

With aging, pain becomes the most exhausting experience. Consistently, many individuals look for treatment for shoulder, knee, back, or hip problems. Similarly, the amount of surgeries being performed has been on the rise, and entire knee and hip replacements rank among the most usually performed orthopedic treatment.  But is surgery the right option?  Before you take that jump, you need to think about the issues related to surgery and why stem cells may be a superior choice for you!  Stem Cell Treatment is cost-effective in the long run.  Both stem cell infusions and surgery are moderately costly techniques. You might like to settle on surgery since medical coverage might take care of the expenses. Your costs might be higher than you envision.  In addition, surgery requires sedation and pre-sedative examinations that can cost you time and cash. The long recuperation time after surgery may likewise bring about missed wages. Henceforth, over the long haul, you mi...
Post a Comment
Read more

What Makes Stem Cells Special And How It’s Beneficial? | Dr. David Greene Arizona

  The introduction of stem cell therapy has given a lot of patients relief from their long-term problems. This treatment has given medical experts, practitioners, and patients a new hope or a way to treat diseases or injuries. Many experts in stem cell therapy like   Dr. David Greene Arizona , think that this treatment will improve the traditional medical methods to treat illness and injuries. To perform stem cell therapy, medical experts require stem cells as the first objective. There are two sources of it, first from adult body tissue and second from embryos. Still, medical experts are trying other ways to develop stem cells. Stem cells are the only cells in our body that can divide and grow into other cells (skin, cardiac, brain cells).  Medical Conditions Supported By Treatment More involvement in stem cell study in healthcare has shown that it is an effective way to treat illnesses, injuries, and chronic diseases. Even the latest studies focus on exploring medical c...
3 comments
Read more

When it is Time to See ENT Doctor - David Greene MD

With all the infections bobbing around, it's normal to have a runny nose but if you're continually going after a tissue for longer than two weeks, it's a smart thought to see a doctor such as Dr David Greene MD to figure out what's happening. Your nose will run when there is overabundance waste delivered by nasal tissues and veins. This can occur because of aggravations and irritation from colds and sensitivities, from a contamination, for example, sinusitis, or from a blockage in the nasal passage. How an ENT Doctor Help You:   An ear, nose and throat specialist can converse with you about your indications and look at you to figure out what's making your nose run. A few conditions and relating medicines ENT David Greene MD can offer include: Allergies: A runny nose and allergies go one by one and allergens make disturbance your sinuses, making your nose run. Allergy medications, for example, immunotherapy will slowly bring the allergen into your immun...
Post a Comment
Read more