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R3 International Stem Cell Therapy for Stroke | Dr. David Greene Arizona

 Arizona based retired orthopedic surgeon Dr. David Greene MD founded R3 Stem Cell in 2013, which has now multiple clinics worldwide and known for its effective, affordable, and safe treatments and results. Today we will discuss stem cell therapies for stroke. 


Stroke is a major cause of death and disability worldwide, with a 1 in 6-lifetime risk. That risk actually doubles for each decade after the age of 55, added Dr. David Greene Arizona. Ischemic stroke accounts for 87% of cases, which is when a blood vessel supplying the brain becomes obstructed. Hemorrhagic stroke occurs when a weakened blood vessel ruptures, such as with an aneurysm or an AVM. 


A transient ischemic attack (TIA) is called a “warning stroke”, as it involves reversible symptoms of a true stroke. 12% of ischemic strokes are preceded by a TIA. Risk factors for stroke include high blood pressure, smoking, oral contraceptives, illegal drugs or alcohol use. 


Symptoms of a stroke may include weakness, vision issues, facial drooping, and speech abnormalities. Usually, a CT or MRI scan will display the extent of the damage. 


Immediate treatments for an ischemic stroke may include clot-busting drugs, thrombectomy, and eventually anticoagulants and possibly a carotid endarterectomy +/- a stent. For a hemorrhagic stroke, a metal clip may be indicated. Traditional treatments for stroke recovery include intensive rehab for months, but after the six-month time frame progression truly slows to a crawl. 


Stem Cell Therapy for Stroke 


Prior to stem cell therapy, no effective biologic has existed to help with the actual repair of damaged brain tissue, mentioned Dr. David Greene. There are several mechanisms of action of stem cells, which include: 

  • Neuroprotection – keeps neurons from getting injured. 
  • Neuroregeneration 
  • Anti-inflammation – helps with the repair. 
  • Immune Modulation – promotes nerve regeneration. 
  • Anti-Apoptosis – prevents cell death. 
  • Angiogenesis – formation of new blood vessels. 


A 2019 Review in Brain Research evaluated 24 patients receiving stem cells through an intrathecal approach up to 11 years out from the stroke. The results were amazing, displaying improved ambulation, hand control, and balance. 


Another study in 2019 evaluated 36 patients receiving 1.5 million stem cells per kg up to 8 years after a stroke. The results were tremendous, with the vast majority of patients seeing significant functional and behavioral benefits. There were no significant adverse events. 


R3 Stem Cell International offers safe and effective stem cell therapy for stroke patients, whether the stroke was recent or years prior. We have seen excellent outcomes using a combination of intravenous and intrathecal application, with each patient being evaluated individually to see if he or she is a candidate. 


Stem cell dosing depends on patient weight, ranging from 50 million up to 200 million stem cells R3 also adds in exosome therapy for additional benefits. 


Over the past decade, R3 Stem Cell’s Centers have performed 16,000 stem cell procedures globally, added David Greene Orthopedic. No clinics around the world are able to offer the combination of quality stem cell biologic, very high cell counts, and cost-effectiveness as R3 Stem Cell. In addition to stroke, R3 effectively treats over 70 conditions such as orthopedic, autoimmune, neurologic, autism, organ failure, and more. Contact us today by calling +1 (888) 988-0515.

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